Yes, but the big western publishers aren't going to support it.
At this point the future of handheld devices is going to be phones and tablets that stream games, unfortunately. So if by new handheld you mean a phone with DS4 buttons like the old Xperia's yes, absolutely.
This isn't EA or something. Bethesda has released more single player focused games than any other big publisher outside Sony. They aren't without their faults but at least give credit where due.
"And since then, no official word that the PC version had been cancelled."
Let me correct you, no one since that single mention in 2015 has said it will be on PC. I'd also like to remind you that was basically pre-production at that point.
Haha you guys are so desperate it's almost adorable.
Because Kojima has made games that are considered to be some of the very best games every generation since the 80's. He has basically never made a bad game.