Good point re the 1 to 1000 years and lets hope EA remembers that Asari can live 1000 years and Krogan can also live many hundreds of years also.
Hence if it is a sequel even if not related to Shepard directly they have to be careful not to write everyone out as that could bite them in the ass re the time line.
I want EA to come out and admit that Synthesis and Control in ME3 were elements of Shepard's mind falling apart under indoctrination. We all know that's what it was and confirm that destruction was the result of Shep fighting his/her way past the AI and completing his/her mission to destroy the Reapers ! After all why have that N7 body take a breath. We can then sit back and enjoy the sequel.
Any game that has resurrection can reinvent itself anyway it wants after all it is S...
There seems to be absolutely no reliable intel out there and no one even breaking cover to leak details on the next instalment of Mass Effect - Seems EA must pay it's staff too well. Of course older style reporters used to get up off their chair and away from their PC and go and canvass peeps for input........
He/she did in the mode 'destruction' hence the body that breathes clip in the aftermath. Everything else was indoctrination as expect that to be the line eventually in some future download if not in the actual ME4 game release.